Best of this week

Medical Review by: Prof. Dr. Soner Tatlıdede – September 2026 17-Alpha Estradiol (commercially known as Alfatradiol or Pantostin) is a topically applied stereoisomer of the female sex hormone 17-Beta Estradiol. Unlike its systemic isomer, 17-Alpha Estradiol exhibits minimal systemic estrogenic activity (approximately 1/100th of the binding affinity to classical estrogen receptors). When applied topically to the scalp […]

Medical Review by: Prof. Dr. Soner Tatlıdede – September 2026 Undergoing cancer treatment brings significant physical and emotional challenges. Among the various side effects, hair loss (alopecia) remains one of the most distressed symptoms for patients. However, a widespread misconception among patients and their families is that all cancer treatments affect hair growth in the exact same […]

Medical Review by: Prof. Dr. Soner Tatlıdede – September 2026 The Evolution of Minoxidil in Alopecia Therapy Minoxidil holds a unique place in modern pharmacological history. Originally developed in the 1970s as an oral antihypertensive treatment for severe high blood pressure, clinicians soon observed an unexpected secondary effect among patients: generalized hypertrichosis (excessive hair growth). Recognizing its medical […]

Medical Review by: Prof. Dr. Soner Tatlıdede – September 2026 Modern Hair Restoration Meets Surgical Precision Deciding to undergo hair restoration is a transformative step toward regaining self-confidence, hair density, and a youthful appearance. Over the past two decades, technological advancements have transformed hair transplantation from an aggressive surgical procedure into a refined, minimally invasive micro-surgical art. Today, […]

Medical Review by: Prof. Dr. Soner Tatlıdede – September 2026 Androgenetic alopecia (genetic male pattern baldness) is primarily driven by the hormone dihydrotestosterone (DHT), a potent byproduct of testosterone. The conversion of systemic testosterone into DHT occurs locally within tissue microenvironments via the action of the enzyme 5-alpha reductase (5-AR). When DHT binds to androgen receptors located in […]

Medical Review by: Prof. Dr. Soner Tatlıdede – September 2026 Biotin, historically known as Vitamin B7 or Vitamin H, serves as an essential coenzyme for five key carboxylase enzymes (ACC1, ACC2, PC, PCC, and MCC) within human cellular mitochondria. These carboxylases are responsible for catalyzed carboxylation reactions crucial for fatty acid synthesis, gluconeogenesis, and the catabolism of branched-chain […]